cross-referenced news and research resources about
estrogens (oestrogens)
Estrogens or Oestrogens, are a group of compounds named for their importance in both menstrual and estrous reproductive cycles. They are the primary female sex hormones. Natural estrogens are steroid hormones, while some synthetic ones are non-steroidal. The name comes from the Greek οἶστρος (oistros), literally meaning "gadfly" but figuratively sexual passion or desire, and the suffix -gen, meaning "producer of".
Estrogens are synthesized in all vertebrates as well as some insects. Their presence in both vertebrates and insects suggests that estrogenic sex hormones have an ancient evolutionary history.
Estrogens are used as part of some oral contraceptives, in estrogen replacement therapy for postmenopausal women, and in hormone replacement therapy for trans women.
Like all steroid hormones, estrogens readily diffuse across the cell membrane. Once inside the cell, they bind to and activate estrogen receptors which in turn modulate the expression of many genes. Additionally, estrogens have been shown to activate a G protein-coupled receptor, GPR30.
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updated Sun. July 14, 2024
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Dove Medical Press
March 29, 2018
Objectives: Depressive symptoms are common during pregnancy and after childbirth. Estrogen levels fluctuate greatly during the course of pregnancy and may contribute to mood instability. The first aim of this case–control study was to investigate whether variants in the two estrogen receptor genes mightÃâà...
Cancer Network
March 28, 2018
New data are suggesting there is phenotypic and molecular interplay between estrogen receptor (ER) alpha and glucocorticoid receptor (GR) in endometrial cancer, which may be affecting outcomes. In an article published in the journal Cell Reports, researchers reported these two receptors areÃâà...
CNN
March 28, 2018
Welcome to life without estrogen. "Preclinical data has shown that either surgical menopause or declines in estrogen accelerates fat accumulation, primarily visceral or abdominal fat," said Dr. JoAnn Pinkerton, executive director of the North American Menopause Society. "Changes over time in how womenÃâà...
News-Medical.net
March 28, 2018
Testosterone therapy is not associated with a rise in estrogen levels among transgender men, according to a new study led by Boston Medical Center (BMC). In fact, the researchers observed an initial decline in estrogen levels, which later stabilized and remained within the normal range during the study'sÃâà...
Medical Daily
March 28, 2018
The present guidelines for the treatment of transgender men using testosterone therapy state that there might be a need to include estrogen-lowering strategies such as the removal of the uterus or ovaries. But a new study led by Boston Medical Center (BMC) suggests that testosterone therapy is not linkedÃâà...
KHQ Right Now
March 20, 2018
CHICAGO (AP) - In a study of women with menopause-related sexual discomfort, gels worked as well as prescription hormone tablets at reducing symptoms. The researchers say the results suggest low-cost, over-the-counter moisturizers might be the best option. Most women reported some relief from theirÃâà...
The Massachusetts Daily Collegian
March 20, 2018
Soy contains very concentrated amounts of isoflavones—a chemical compound that acts very similarly to estrogen in the human body due to its similar chemical structure. So, while soy may not raise estrogen levels directly, it effectively provides an additional influx of estrogen-like compounds that canÃâà...
Science Daily
March 19, 2018
Researchers at the NIEHS, including Kenneth Korach, Ph.D., a co-investigator for the new study, previously found laboratory evidence that lavender and tea tree oil have estrogenic (estrogen-like) properties and anti-androgenic (testosterone inhibiting-like) activities, meaning they compete or hinder theÃâà...
India Today
March 19, 2018
"Female athletes with exercise-induced menstrual dysfunction (associated with low estrogen levels) often have disordered eating behaviour, which may impact their reproductive and bone health," lead researcher Madhusmita Misra of Massachusetts General Hospital in Boston, Mass told ANI.
Endocrinology Advisor
March 19, 2018
In young female athletes with oligo-amenorrhea, estrogen replacement therapy may improve disordered eating behavior and psychopathology by normalizing estrogen levels, according to an abstract presented at ENDO 2018: The Endocrine Society Annual Meeting, held March 17-20 in Chicago, Illinois.1.
Science Daily
March 19, 2018
Giving one year of estrogen replacement to female athletes with exercise-induced menstrual irregularities improves drive for thinness, body dissatisfaction and uncontrolled eating, a new study finds. The research results will be presented Saturday, March 17, at ENDO 2018, the annual scientific meeting ofÃâà...
Healio
March 18, 2018
CHICAGO — Young female athletes with normal weight and no or irregular menstrual periods reported fewer disordered eating behaviors, diminished drive for thinness and less body dissatisfaction after receiving 12 months of estrogen therapy, according to findings of a cross-sectional study and aÃâà...
KABC-TV
March 5, 2018
Acupuncture is one of many alternatives to estrogen therapy for women going through menopause. (KABC) ... While healthy women - who aren't at high risk for heart disease or cancer - may be able to take estrogen therapy safely, there are non-HRT medications she recommends for hot flashes. One is aÃâà...
News-Medical.net
March 1, 2018
Two University of Houston researchers, working to find cancer cures, received grants from the Cancer Prevention & Research Institute of Texas (CPRIT), the organization that funds groundbreaking cancer research and prevention programs in the state. CPRIT awarded $1,173,420 to Navin Varadarajan,Ãâà...
Yale News
March 1, 2018
Nerve cells in cognitive regions of the brain that are earliest affected by Alzheimer's disease depend on estrogens for proper functioning. The precipitous loss of estrogens at menopause leaves these cells more vulnerable to the detrimental effects of the disease. Although estrogen treatment can reverseÃâà...
Psychology Today (blog)
December 31, 1999
By the time a woman is in her 50's, there are very few eggs left in the ovaries, and consequently, there are significantly decreased or even undetectable levels of estrogens and progesterone in the body. After the menopause (defined as 12 consecutive months with no menstrual period), when there are noÃâà...
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