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 biological molecules

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updated Mon. February 4, 2019

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The other is a benzoate molecule which self-assembles into sheet-like nanostructures. These sheets form molecular "bricks", ... In the future, the Bioinspired Soft Matter Unit hopes to construct specific molecules on biological membranes to regulate cell fates. For instance, by building molecules on cell ...
The new research shows that HIV targets and disables a pathway involving a number of biological molecules that are key in blocking viral activity and ... During any viral infection our immune system produces a powerful molecule (Interferon), which 'interferes' with the infection and the replication of viruses.

BIO supports research to advance our understanding of the principles and mechanisms that govern life itself. The research studies of BIO extend across systems that encompass biological molecules, cells, communities, tissues, organs, organisms, populations and ecosystems up to and including, the global ...
The researchers found that a class of molecules called sulfidic anions may have been abundant in Earth's lakes and rivers. They calculate that, around 3.9 billion years ago, erupting volcanoes emitted huge quantities of sulfur dioxide into the atmosphere, which eventually settled and dissolved in water as ...
“In shallow lakes, we found these molecules would have been an inevitable part of the environment,” says Sukrit Ranjan, a postdoc in MIT's Department ... would have mostly stayed in the atmosphere, as the molecule is relatively insoluble in water, and therefore would not have had regular opportunities to ...
A coupled system of two miniature detectors called nanopores improves detection of biological molecules, including DNA and markers of early disease. ... This process results in each molecule producing a unique signature, without the need for lengthy sample preparation or chemical modification. However ...

We're in an exciting new era of cancer treatment – where biological molecules are allowing us to target tumors and the surrounding host biology in an ... Dr James Allison of MD Anderson Cancer Center identified CTLA-4 as an inhibitory checkpoint molecule, which restricted activated T-cell responses.
Elena Rybak-Akimova, a chemist at Tufts University who studied how activated oxygen molecules drive biological processes, died of cancer this week (March 11) at age 56. “She was a fearless scientist,” Krishna Kumar, the Tufts Chemistry Department Chair, says in a statement. “The community recognized ...
... are broken down during signal transfer, the cell must renew its stock of messenger molecules quickly and efficiently to maintain its signaling networks. ... from the National Centre for Biological Sciences (NCBS), Bangalore, now shows that the regeneration of a membrane-bound messenger molecule, ...
To better understand these processes, in which calcium ions interact with biological molecules such as proteins, researchers often use computer simulations. ... Typically, interactions with water molecules work to pull a calcium ion away from the molecule it's trying to bind with, like in a molecular tug of war.
But applications of the method go beyond just imaging biological molecules. Sarah Li from the University of Utah thought it could be useful for optimizing semiconductors or other microscopic-scale electronics. Essentially, this is a fundamentally different way of characterizing things on the smallest scale.
There are various levels of organization in biological molecules. For instance, proteins are composed of amino acid sequences and then they get assembled into different domains. Proteins with different functions and localizations in cells of several different organisms can possess the same domains.
This new molecule, recently described in the journal Angewandte Chemie International Edition, expands the biological applications for nanocarbons, including cancer cell imaging and possibly eradication. Nanographenes, nano-sized carbon molecules, exhibit unique electronic, optical and mechanical ...
Researchers from Queen Mary University of London have developed a 3D bioprinting method that enables the creation of biological structures from cells and molecules that are commonly found in natural tissues. From human skin to ears made from a patient's own cells, 3D bioprinting has changed the landscape of medical ...
Professor Alvaro Mata, from Queen Mary's School of Engineering and Materials Science, said: "The technique opens the possibility to design and create biological scenarios like complex and specific cell environments, which can be used in different fields such as tissue engineering by creating constructs ...
A longstanding mystery in biology is how the millions of molecules bumping around in a cell "find" one another and organize into functional structures. So it was a big surprise in 2008 when participants in the Marine Biological Laboratory (MBL) Physiology course realized that simple phase separations ...
Ahead of the 2018 EuCheMS Chemistry Congress, we chat to plenary speaker Christopher Dobson about the international nature of science and the cultural experiences it opens up. Professor Christopher Dobson CChem FRSC FRS FMedSci leads a research group at the Unviersity of Cambridge ...

The other library contains kinase inhibitors that have been tested in clinical trials and have known biological activity. ... The group selected from each library the molecule with the best capacity to bind to the target kinases, and they then crystallized the complexes formed by the inhibitors and kinases so that ...
In a previous study published in Nature Cell Biology, RCGD 423 was shown to activate stem cells to make hair grow. The lab is partnering with scientists at USC and beyond to explore the broader potential of these molecules to treat rheumatoid arthritis, jaw arthritis, lupus, neurological and heart diseases ...
The synthetic cells are artificial systems with capacities similar to, and, at times, superior to those of natural cells. Just as human cells can generate a variety of biological molecules, the synthetic cell can produce a wide range of proteins. Such systems bear vast potential in the tissue engineering discipline, ...
Additionally, the study looked at the way that quantum effects might aid the olfactory ability to recognise smells from molecules, through a process known as 'quantum tunneling', which helps a smell molecule unite with a receptor. This understanding holds out the prospect of developing technologies for ...
Understanding of the biological mechanisms of aging has progressed markedly in recent years. For example, it is now known that the processing of messenger RNA (mRNA) has been implicated in lifespan. mRNA are the molecules that transfer the “genetic code” from DNA for the creation of proteins.
The yellowish-white creamy substance has been demonstrated to possess a number of biological properties, such as antimicrobial (2,3), ... however, the majority of the constituents of royal jelly such as amino acids, sugars, and vitamins are small molecules with hydrophilic properties (1), not retained in ...
Single-molecule detection can reveal time trajectories and reaction pathways of individual intermediates/transition states in chemical reactions and biological processes, which is of fundamental importance to elucidate their intrinsic mechanisms. We present a reliable, label-free single-molecule approach ...
Advances in technology have finally allowed researchers to measure the amount of a rare form of nitrogen molecule in our atmosphere, which it turns out ... Most of the atoms in those molecules have an atomic mass of 14. ... One possible source of these double nitrogen-15 molecules could be biological.
Unlike biological ion channels, however, this selectivity comes from the removal of water molecules only, a process known as dehydration. Graphene nanopores will allow this dehydration-only selectivity to be measured under a variety of conditions, another new feat. The researchers reported their findings ...
It's only through this collaboration that we'll be able to develop new technologies to find the incredibly small signals emitted by early tumours and to extract these signals from the sea of normal, healthy biological molecules. Biologists have made incredible advances in helping us understand the early ...
The NAN enables both a small molecule drug and a nucleic acid – RNA or DNA – to be delivered to a cell. This combination generates a nanocapsule capable of shepherding genetic or pharmaceutical molecules to a target on or within a cell. Once guided to their target, the encapsulated materials are ...
Chemists have gotten a lot of mileage out of the Nobel-Prize-winning, light-activated motor molecules invented in Ben L. Feringa's lab at the University of Groningen. Feringa has used them to create molecule-sized cars that scoot along a surface, and others have incorporated them into polymers or used ...
Kumar and his team have, for the first time, created quantum entanglement from a biological system. ... The team attempted to entangle the photons generated from the fluorescing molecules within the algae's barrel-shaped protein structure by exposing them to spontaneous four-wave mixing, a process in ...
By modeling biological molecules over longer timescales, a new algorithm can help better understand diseases ... challenges to these methods is in defining the coordinates that describe the system—which, for example, can be the length between atoms in the molecule, and the angles between bonds.
Speeding up processing time to elucidate highly complex study systems like the dynamics of biological molecules has been a common challenge. Now, scientists have developed a practical solution to the problem of saving time when using computer simulations that require bringing a complex system into ...
The standard method for profiling the transcriptome of a biological sample is by RNA sequencing (RNA-seq), whereas fluorescence in situ hybridization ... Data obtained using RNA SPOTs showed high concordance with RNA-seq data transcriptome-wide, as well as with single-molecule FISH results for ...
The first thing that pushes a molecule aside is the maker of the sound. Anything that moves produces a sound, although it may be very slight. That's probably why there seems to be so much commotion. Everyone and everything is moving around too much. Just sit still for a little while and be quiet. It will help ...
The team also showed that the graphene tweezers could be used for a wide range of physical and biological applications by trapping semiconductor nanocrystals, nanodiamond particles, and even DNA molecules. Normally this type of trapping would require high voltages, restricting it to a laboratory ...
Then the company uses its software platform to run trillions of possible molecules and come up with a handful of ones that may work for the job. Because proteins are so complex, they can't just be cooked up in a beaker. Instead, Arzeda codes genetic material that instructs a cell on how to make the protein.
DNA sequencing, which determines the precise order of nucleotides contained in biological molecules, can be used to map individual genes or entire genetic regions. Since its inception in the 1950s, sequencing has been incorporated into medicine, evolutionary biology and other bioscientific fields, ...
Scientists have expanded the building blocks of DNA to create a stable semi-synthetic organism that can produce biological compounds entirely new to ... new nucleotide transporter to enable better DNA replication, an optimised Y molecule, and a refined engineering system making use of CRISPR-Cas9.
Microbes can use proteins and small molecules to communicate with one another as they form large communities, and similarly, host cells can secrete molecules that allow them to ... This approach uses small-molecule probes that can bind to specific proteins based on their biochemical activity. We were ...
Innovative biological approaches and the discovery of new biological molecules are changing the therapeutic approach and increasing the chances of healing. Cancer cells are able to elude physiological control and grow in uncontrolled manner. In fact, groups of "pro-tumor" proteins can get activated and ...
In biological systems, molecules can bind to the surface or interior of proteins, which helps make them stable. ... The team found that their best version of the crown ether molecule, which they called TC7, was a non-sticky powder when dry, but formed a strong adhesive when a small amount of water was ...
NASA Astronomers Search Alien Planets for "Biologically-Friendly Molecules With Strong Infrared Emitting Power" ... reactions that ultimately produce what the scientists call atmospheric beacons: hydroxyl, more molecular oxygen, and nitric oxide—a molecule made of one nitrogen and one oxygen atom.
... on analyzing the patterns of light that bounce off a crystallized molecule. ... She had used it to explore the structures of biological molecules ...
The other type is a double-stranded helical molecule of DNA chosen to react with the metabolite signal — glucose — and initiate the chemical ...
With a clearer picture of the structure of biological molecules, drug researchers now have a much better idea of the chemistry going on inside ...
The Levels Of Biological Organization In The Body ... a molecule, with one or more chemical bonds holding the molecule together. A large amount of the molecules that are important to living things are called macromolecules.
Quest to depict CG sperm leads to real biological advances ... make up the tail and the “dynein” molecules lined up between them, the known ... Additionally, while previous studies of dynein have revealed the molecule's two ...
A larger surface area allows the molecules in wine to diffuse into the air, ... b) dealing with sediment — basically masses of biological molecules ...
... was for their ground-breaking discovery of a technique called cryo-electron microscopy, which can be used to visualise biological molecules.
Many important biological functions depend on a process called glycosylation, which is the attachment of sugars to other molecules such as ...


 

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biological molecules