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updated Mon. March 4, 2019

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Exosomes enable transmission of macromolecules and intracellular communication between cells of membrane, cytosolic proteins, lipids and RNA by serving as vehicle of transfer. Recently they have been identified as useful vectors as they are composed of cell membrane instead of synthetic polymers ...
The torsional conformation of the backbone of a π-conjugated macromolecule influences its shape, solubility, optoelectronic characteristics, rheological behavior, and ultimately solid-state functions. In order to tailor these molecular, supramolecular, and materials properties, the desired coplanar ...

Methyltransferases are enzymes that transfer methyl groups to certain building blocks of macromolecules such as DNA (deoxyribonucleic acid, carrier of genetic information), RNA (ribonucleic acid, transmitter of genetic information) and also proteins (products of the genetic information), and hence ...
Nobel Laureate Joachim Frank, a former scientist at the state's Wadsworth Center in Albany, will be speaking Thursday afternoon at the Albany Capital Center on Eagle Street. The state Department of Health is hosting the 1 p.m. event, which will include a lecture by Frank, a Columbia University professor ...
The team reported on a series of novel hyperbranched macromolecules with, at most, 15 mechanical bonds at the branching unit. Mechanical bonds are a novel and exciting class of non-covalent bonds similar to familiar chains and hooks, for example. These macromolecules can induce an overall ...
In solution, these macromolecules are intricately entangled with each other, like the fibers in clumps of fluff. In the 1970s, a model was ... In this way, the model captures how the mobility of each individual macromolecule is restricted by the spatial distribution of all the others. In this picture, the only way to ...

As an important method in structural biology, cryo-EM allows the observation of the structure of bio macromolecules such as nucleic acids and proteins. In contrast to X-ray crystallography and magnetic resonance imaging, cryo-EM allows high-resolution 3D imaging without damaging the structures of the ...
Symic Bio is a biopharmaceutical company developing novel matrix-targeting biotherapeutics, a new category of therapeutics focused on matrix biology. These biotherapeutics, with potential applications in a wide variety of disease states, are inspired by naturally occurring macromolecules that play key ...
Nanda and colleagues began the search for these ancient proteins using 3D data from the vast RCSB Protein Data Bank, a global archive that contains the 3D structures of nearly 140,000 biological macromolecules, rendered in atomic-level detail. "We don't have a fossil record of what proteins looked like ...
Serving as pipelines throughout the body's organs and tissues, epithelial tubes have important physiological roles, from the delivery of essential gases, liquids, and macromolecules around the body to the elimination of metabolic waste. These structures are formed in the earliest stages of embryonic ...
When DNA from the animals' hippocampus (which processes memory) was later analysed, the researchers found that chromatin – macromolecules that help 'package' DNA inside cells – had become more accessible. With a new bioinformatics tool they developed called DEScan (Differential Enrichment ...
The two-member team, led by Dr. John Philip from the Metallurgy and Materials Group, used a magnetic nanofluid emulsion (oil droplets finely dispersed in water) attached with certain macromolecules (polymers) for detecting urea. The polymer attached to the oil droplets appears like a ball with a shock of ...
... Monahans have been found to contain carbon-based compounds. Scientists from the United Kingdom, the United States and Japan studied millimetre-size blue salt crystals inside the meteorites that fell in 1998 in Morocco and found a mixture of carbon-, oxygen- and nitrogen-bearing macromolecules in ...
When biological macromolecules like proteins or polysaccharides are added to the solution mix, the formation pathway can be drastically altered. If the added macromolecules mediate nanoparticle interactions in a way that causes them to assemble with crystallographic alignment, the result is a composite ...
The interactions of biological macromolecules such as nucleic acids, proteins, and polysaccharide-protein conjugates can be mimicked by artificial ... then polymerized in the presence of a presynthesized polyion of opposite charge and another macromolecule serving as an uncharged copolymer block.
Structural techniques such as x-ray crystallography and electron microscopy give insight into how macromolecules function by providing snapshots of ... FRET efficiencies also carry very precise information on the actual distance between fluorophores attached to distinct moieties of a macromolecule.
The effect of these macromolecules on chronic biofilm causing pathogens like E. coli, Acinetobacter, Klebsiella were studied and the results ...

Chemistry Professor Timothy Long, director of the Macromolecules Innovation Institute (MII), and Maruti Hegde, then a postdoctoral researcher ...
Liquid-crystal polymers comprise molecules with high molecular mass, called macromolecules. They are comb-shaped, which implies that ...
"The extent to which we can vary and control physico-chemical characteristics and biological behavior of macromolecules, which are based on ...
The hybrid lipid-protein material, called a lipoproteoplex, comprises both a coiled supercharged protein macromolecule and a commercially ...
Because the researchers engineered the protein macromolecule with extensive positive charges on the surface and a hydrophobic core, it can ...
Within individual cells, there exist thousands of different types of macromolecules, or organic compounds. These will be different, even among ...
... Chem 222) will be replaced with Chem 202: Foundations of Reactivity, Chem 203: Advanced Reactivity and Chem 204: Macromolecules.
For the past year, researchers at the College of Engineering and College of Science were able to synthesize the macromolecules, making them ...
"The use of proper inhibitors, selective for key steps in the biosynthesis of cellular macromolecules in general, may repair normal dynamics in the autolysosomal section and rectify the pathological storage that is the ultimate reason of these types of ...
Current technology for imaging DNA and other genetic material relies on special fluorescent dyes to enhance contrast when macromolecules are imaged. These dyes may perturb cell function, and some eventually kill the cells -- undesirable effects in ...
For decades, textbooks have stated that macromolecules within living cells, such as DNA, RNA and proteins, do not have visible fluorescence on their own.
Thus, discovery of new modalities allowing the effective delivery of drugs and bio-macromolecules to the central nervous system (CNS) is of great importance for the treatment of neurodegenerative disorders.
Proteins are essential macromolecules that are made up of a sequence of amino acids, which fold up in three-dimensional space to create the structure of the molecule.
The surfaces of these "bare" CNPs were then coated with a variety of cationic, or positively charged, macromolecules, such as branched polyethylenimine (PEI), polypeptidic poly L-lysine (polyLys) and dendritic poly amidoamine (PAMAM+), in order to ...
"India is in need of manpower for scientific explorations and discoveries for which youngsters should be motivated to undertake research," he said adding India was the second largest macromolecule depositor in protein data bank as well as utilising the ...
The discovery is significant for understanding physical, biological and chemical processes involved in drug design, functions and synthesis of macromolecules, and may even provide clues in the prevention of Alzheimer's disease. Fundamentally, the ...
This mechanical deformation creates transient pores in the carrier membrane to enhance the membrane's permeability to macromolecules and promote the efficient uptake of drugs. Scientists are now developing a model for vesicle squeezing that can be ...
These extracellular structures consist mainly of macromolecules that are secreted by the cell. The chemical nature of the macromolecules differs among organisms but the extracellular structures of most eukaryotes have a common theme - they contain ...
"Mike Chopp is world-renowned and is looking to develop exciting treatments in stroke and TBI using vesicles released by cells that contain cellular macromolecules to stop disease processes," Lapointe said. But researchers readily acknowledge one of ...
... of mutation are induced by cancer-causing events; differentiating benign and malignant tumors; mapping of tumors at the molecular and cellular levels; new ways to target the regulator gene Myc; and the delivery of biologically active macromolecules.
Prof Wuthrich, an expert in Nuclear Magnetic Resonance(NMR) spectroscopy methods for studying biological macromolecules was awarded the Nobel Prize in Chemistry in 2002.
Wuthrich was awarded Nobel in chemistry "for his development of nuclear magnetic resonance spectroscopy for determining the three-dimensional structure of biological macromolecules in solution" in 2002, the CCMB said. 'Personalised medicine' is an ...
Wuthrich was awarded Nobel in chemistry "for his development of nuclear magnetic resonance spectroscopy for determining the three-dimensional structure of biological macromolecules in solution" in 2002, the CCMB said. 'Personalised medicine' is an ...
Wuthrich was awarded Nobel in chemistry "for his development of nuclear magnetic resonance spectroscopy for determining the three-dimensional structure of biological macromolecules in solution" in 2002, the CCMB said. 'Personalised medicine' is an ...
Wuthrich is a Switzerlandbased chemist who was awarded the Nobel prize in 2002 for his contribution to the development of nuclear magnetic resonance spectroscopy for determining the 3D structure of biological macromolecules in solution. He will be ...
Nogales' research is dedicated to visualizing cellular macromolecules using cryo-electron microscopy (cryo-EM) as her main experimental tool.
Headed by Donald Ronning, the team who studied the HpMTAN found out that the H. pylori uses a unique biosynthetic pathway to synthesize vitamin K2, a vitamin which catalyzes the HpMTAN's interaction with other macromolecules which also leads to ...
... to correctly identify the mechanism that led to the congealing as a polymerization process and a further 80 more years past that (1949) before the German organic chemist Hermann Staudinger proposed his theory of a macromolecule chain reaction.
Aging is a assembling of impairment to macromolecules, cells, tissues and organs. If any of that damage can be fixed, the outcome is rejuvenation.
"We also demonstrated that sequencing instruments could still work even when they're not being coddled in an indoors lab, which opens up a whole bunch of opportunities for doing macromolecule analysis in places like Mars." Bai, the only undergraduate ...
Beckman Coulter Life Sciences returns analytical ultracentrifugation (AUC) to the center of protein research and macromolecule characterization with the next-generation Optima AUC. The instrument is now available for use in labs around the world, and ...
The arrival of the new hardware means University of Leeds scientists are now in a position of being able to study bacteria, viruses, and the macromolecules that dictate the life and health of our cells at near atomic level in three different ways ...
Vitamin K2 acts to expedite the HpMTAN enzyme's interaction with other macromolecules, including the very bacterium that causes an array of gastric health issues.


 

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