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 ebola virus

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updated Tue. April 17, 2018

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But how long that protection lasts remained an open question. A fast-acting, long-lasting vaccine given in a single dose would be an effective tool for controlling dangerous Ebola outbreaks. Vaccinating health care workers, for instance, could prevent the type of spread within hospitals that, in the early ...
The Ebola virus destroyed more than human lives when it emerged in Guinea a few years ago--it also eroded agriculture in Guinea, Liberia, and Sierra Leone. Food shortages, trade restrictions, border controls, and rising food prices led many farmers to resort to desperate measures and eat the seeds ... Ebola

An Ebola vaccine made by Merck has protected a group of volunteers for two years -- the longest it has been shown to protect against the disease, according to a study published in Lancet Infectious Diseases. The context: "A fast-acting, long-lasting vaccine given in a single dose would be an effective ...
April 16th, 2018 - There were several Ebola virus vaccine candidates developed during the 2013-16 western Africa outbreak. These vaccines were reported in a previous study to be well tolerated and immunogenic. However, health officials questioned the longevity of immune responses induced by ...
Along with causing 11,000 deaths, the 2014 to 2016 West Africa Ebola virus disease outbreak severely impacted health systems and cost Guinea, Liberia and Sierra Leone an estimated $2.8 billion. A key lesson in the response to this outbreak was the critical importance of engaging with and ...
Former President John Dramani Mahama has said that the outbreak of the Ebola virus in three West African countries affected tourism in several other West ... Mr Mahama noted that "when Ebola struck recently in three of our sister countries in the sub-region, it affected tourism arrivals in all our countries". West Africa

Scientific evidence at the start of the last major Ebola epidemic in West Africa that suggested the virus would change exceptionally rapidly was probably due to methodological biases. This has been shown by scientists led by Tanja Stadler, a professor at ETH Zurich's Department of Biosystems Science ...
The 2014-2016 West African Ebola outbreak was the deadliest in history, infecting more than 28,000 people and killing more than 11,000. While the number of people infected in the United States was low, it was covered extensively in the media, leading to widespread fear. Now, given the success of recent ...
Researchers were able to mutate Viral Protein 40 (VP40) in a way that changed the residues of the protein, blocking the budding and replication of Ebola virus in a model system. VP40 is a peripheral membrane protein that regulates viral budding from the plasma membrane. It interacts with a human ...
Dr Matthew Snape, Consultant Vaccinologist at the Oxford Vaccine Group, University of Oxford said: “The extraordinary response to the Ebola virus epidemic of 2013 to 2015 included rapid development of several potential vaccines against this deadly virus, many of which had their 'first in human' dose ...
University of Alberta researchers have found the Ebola polymerase (enzyme), which may lead to more effective research and better treatments for the often fatal infection, and other related viral diseases. "Our study reports the expression, purification and biochemical characterization of an active, ...
Thanks for visiting HeraldMailMedia.com. You're entitled to limited access of articles every 30 days. If you enjoy our site and want full access, we ask you to purchase an affordable subscription. Facebook · Twitter · Email; Print; Save. WINCHESTER, Va. — A "safety zone" has been set up for the care of a ...
Now, University of Guelph researchers have shown that an innovative antibody delivery method could offer an effective way to prevent and treat Ebola infection. “Our goal is to make an antibody-based therapy that can protect against all strains of Ebola, and potentially Marburg virus, as well,” says Prof.
"Our goal is to make an antibody-based therapy that can protect against all strains of Ebola, and potentially Marburg virus, as well," says Prof. Sarah Wootton, Department of Pathobiology, who, along with PhD student Laura van Lieshout, found a new way to fight Ebola. "It would be used to stop the spread ...
... who contracted Ebola to take a drug that wasn't yet approved. It's the latest salvo in a legal case that could have broader implications for the ongoing campaign to pass a federal “right-to-try 1” law, in which advocates are aiming to help dying patients get access to other drugs the FDA hasn't yet approved.
Sierra Leone was among the countries hardest hit by the December 2013 Ebola outbreak, along with Guinea and Liberia. It recorded more than 3 900 of the 11 300 deaths from the more than two-year epidemic, according to the World Health Organisation. The outbreak led to schools being closed between ...
A new study says more than 100,000 malaria cases went untreated in Liberia during the height of the Ebola crisis. The deadly virus spread in West Africa for two years beginning in 2014. The disease killed about 11,000 people. But it also severely affected basic health care services. Ebola kills about half of ...

We learned this in 2014, with the Ebola crisis. While Ebola is fairly hard to catch, it left more than 11,000 people dead — and served as an enormous wake-up call. Republicans and Democrats in Congress put down their partisan swords. Senator Lamar Alexander (R-TN) told a crowded hearing room on ...
ZMapp functions as a combination of 3 humanized antibodies produced in genetically-modified tobacco plants that target 3 Ebola glycoprotein epitopes. If it proves efficacious and safe in animal models, it could be on track to become the first Ebola treatment approved by the US Food and Drug ...
Bats provide a refuge for some of the most lethal viruses known, including Ebola, Marburg, Nipah and SARS. Now we may know why the animals tolerate these lethal viruses – and it's because flying is such hard work. Peng Zhou of the Wuhan Institution of Virology in China and his colleagues studied the ...
“Ebola's collateral effects on (Liberia's) health system likely caused more deaths than Ebola did directly,” the university said in a press release. One of the most pernicious effects of the virus was the infection of almost 300 medical staff in Liberia, according to World Health Organization (WHO) figures, limiting ...
More than 100,000 malaria cases went untreated when Liberia's health care system buckled under the 2014-2015 Ebola outbreak, according to a new study. The research, published in the journal PLOS Medicine, shows how the toll of the Ebola outbreak goes beyond the 11,000 killed in West Africa by the ...
Etta Roberts works as a nurse at the Kahweh clinic, a health centre to the east of Monrovia. She usually treats around 10 patients a day for malaria and scabies. The clinic's founder, Reginald Kahweh, funded the building of the centre after losing both his parents to Ebola, saying: "Everyone had to step up to ...
Based on the findings, the authors hypothesize that Ebola virus can persist in these tissues in human survivors, and that the virus may reach seminal fluid in men by infecting immune cells called tissue macrophages. However, it is unclear if the detection of Ebola virus RNA in semen documented in human ...
When the deadly Ebola virus appeared in the Democratic Republic of Congo last year, the first reported outbreak since 2014, a rapid-response health care team snuffed it out quickly. While any triumph over the lethal scourge should be commended, it's also an early warning sign for the United States in an ...
First appearing in Sudan and the Democratic Republic of Congo in 1976, Ebola has instilled fear wherever infections have emerged due to its high fatality rate ranging from 25% to 90%. Most recently, west Africa experienced a record-breaking outbreak in 2014-2016. The virus spreads via the bodily fluids ...
The outbreak was only identified as Ebola three months later, in March 2014, by which time it had killed 30 people. The contagion coursed through the towns and villages of Guinea, then Sierra Leone, Liberia, Nigeria, Senegal and Mali. Infections multiplied at a rapid rate, killing more than 11,000 people. Ebola outbreak
Emergency medical training happens all the time in our area, but an event today (Wednesday) was unusual. It involved a big plane and a big disease, the Ebola virus. This medical exercise started Wednesday morning in Boise, where a 747 took off, headed for Spokane. It was carrying a staff of ... Ebola
Scientific evidence at the start of the last major Ebola epidemic in West Africa that suggested the virus would change exceptionally rapidly was probably due to methodological biases. This has been shown by scientists led by Tanja Stadler, a professor at ETH Zurich's Department of Biosystems Science ...
It's being led by Professor Yoshihiro Kawaoka who has studied the Ebola vaccine for more than a decade. "We currently have no treatment for Ebola and we have to come up with something," said Rebecca Moritz, who is a bio-safety expert with the University of Wisconsin. Ebola is a rare, and deadly virus, ...
A UW-Madison lab next month will start making a vaccine against Ebola virus, which killed thousands in west Africa from 2014 to 2016. ... near UW Hospital, will produce up to 1,000 doses of vaccine for the clinical trial, to be led by Yoshihiro Kawaoka, a campus virologist and expert on Ebola and influenza.
Diseases such as Ebola and Lassa fever are highly contagious and life-threatening. Three years ago more than 11,000 people died of Ebola in West Africa. There is a high risk of new epidemics in the region. Bad news has come from Nigeria to begin the year: The World Health Organization (WHO) has ...
Some Ebola survivors in Sierra Leone say the local authorities have failed them. Officials promised survivors free healthcare, help with food and shelter, psycho-social support and some financial compensation, according to local news reports. Surviving health workers reportedly were promised they would ...
The public health experts I talked to said the money helped aid workers in rural areas establish programs to detect and respond to new outbreaks of Ebola and other diseases. When the funds stop flowing, these programs may well be toast—a dangerous setback not just for their home countries, but for the ...
The recent Zika and Ebola epidemics brought further urgency to the issue of immune privilege. Reports emerged of patients who had these viruses in their semen months after they were originally infected even though the viruses had been cleared from elsewhere in their bodies. In one of the most extreme ...
In the past 17 years we have battled Sars, the Ebola virus, Mers, and more recently the mysterious mosquito-borne Zika virus. These diseases seeming to appear from nowhere and rapidly ravage our populations. One commonality is that they almost always originate in animals before jumping across to ...
A new paper from a group at Oxford gives a good example of how varied that process can be – it's looking at a number of drugs that have been shown to interfere (to some degree) with infection by the Ebola virus. Ebola has been the subject of a number of screens, which you can be sure were run by ...
A paper-based test detects antibodies against Ebola virus. Droplets of blood serum (left) and a solution of antibody-labeled gold nanoparticles (blue and yellow) placed on one end of the strip wick through printed test lines of Ebola antigens (yellow, red, and green squares). If Ebola antibodies are present in ...
The Executive Director, Programme Manager and Finance Officer of The Needy Today, a local NGO, were alleged to have misappropriated Le300 million meant for vulnerable groups affected by the Ebola outbreak in Makeni. According to State Prosecution, Ebola funds were fraudulently withdrawn from ...
Scientists have managed to inhibit the reproduction of ebola virus in laboratory conditions. Whether the breakthrough can translate into an actual drug is an open question, but the good news is that if it can, the product is likely to work on all ebola strains and maybe on some other vicious viruses as well.
To use the platform against Ebola the team engineered a vesicular stomatitis virus pseudotyped with the glycoprotein from the Zaire strain of Ebola (rVSV–zEBOV). This concept maintained the glycoprotein's tertiary structure but meant the researchers didn't need the maximum biosafety facilities required for ...
Just when it seemed that people in Africa were safe again after the devastating Ebola outbreak, we have a new worry. An outbreak of a related virus known as Marburg Virus has begun in a city called Turkana along the Kenya-Uganda border in East Africa. Marburg virus was first identified in 1967 when an ...
"This research represents a major milestone for i-sense and harnesses the power of mobile phones and paper microfluidic tests to rapidly analyse a patient's immune response to Ebola with geo-located information to map disease 'hotspots' in Uganda," said Professor Rachel McKendry, Professor of ...
FEARS over a killer Ebola-like disease in Jamaica are mounting after an eight-year-old boy died of a fever that caused lethal internal bleeding. ... Although the mortality rate for dengue fever is lower than some other viruses, at 2.5 per cent, the virus can cause a far more lethal Ebola-like disease called ...
Scientists at The Scripps Research Institute (TSRI) recently gleaned new understanding into how an antibody neutralizes the Marburg virus, a pathogen with no known treatment that holds the same pandemic potential as the Ebola virus. Previous research indicated that an antibody known as MR191 could ...
UCLA researchers in the Democratic Republic of the Congo sampled the blood of Ebola survivors who had been infected 40 years ago and found they still had immunity against the disease. (Courtesy of UCLA-DRC Health Research and Training Program) ...
Even though it is now three years and seven months since Nigeria experienced the first ever outbreak of the dreaded Ebola virus, where seven persons lost their lives from 19 confirmed cases, it still seemed just like yesterday in the heart of many Nigerians because of the anxiety, uncertainty and shock it ...
Just when it seemed that people in Africa were safe again after the devastating Ebola outbreak, we have a new worry. An outbreak of a related virus known as Marburg virus has begun in a city called Turkana along the Kenya-Uganda border in East Africa. Marburg virus was first identified in 1967 when an ...
Two Ebola survivors are to sue the government of Sierra Leone in the first international court case intended to throw light on what happened to some of the millions of dollars siphoned off from funding to help fight the disease. The case, filed with the regional west African court in Nigeria, alleges that a lack of ...
'When the Ebola virus enters the human cell, its only purpose is to copy itself, fast. First it must copy all its proteins, then its genetic material. But by inhibiting a specific enzyme we rob the Ebola virus of its ability to copy itself. And that may potentially prevent an Ebola infection from spreading', says Professor ...


 

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