Okemah is a city in Okfuskee County, Oklahoma, United States. It is the county seat of Okfuskee County. It is the birthplace of folk music legend Woody Guthrie. Thlopthlocco Tribal Town, a federally recognized Muscogee Indian tribe, is headquartered in Okemah. The population was 3,223 at the 2010 census and about 23 percent of the residents identified as Native American.
Historically occupied by the Osage and Quapaw, who ceded their lands to the United States by 1825, after Indian Removal of tribes from the Southeast United States in the 1830s, this area was assigned to the Creek Nation and specifically, the Thlopthlocco Tribal Town.